Treatment of central precocious puberty using low dose GnRH analogs (GnRHa)

Methods Clinical Records of 17 children (16 girls and 1 boy) were retrospectively analyzed over a period of 24 months (Mar 2012 to Mar 2014). All children satisfied the criteria for precocity based on clinical features, radiological assessment and GnRHa stimulation test. All 16 girls had idiopathic precocious puberty and the only boy had hypothalamic hamartoma. The mean age of presentation was 6. 9 years. All children received GnRHa as monthly injection in an average dose of 190 μgm /kg/month and were regularly followed for evaluation of pubertal suppression, height gain and Bone age advancement.